A NEW DIRECTION in Treating Alzheimer's Disease, Parkinson's Disease and Other Neurodegenerative Disorders
About Us
Our lead compound buntanetap (formerly known as Posiphen or ANVS401) attacks neurodegeneration by reducing multiple neurotoxic proteins, therefore improving axonal transport, the information highway of the nerve cell, which has been shown to be the cause of nerve cell degeneration and ultimately death.
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With an aging population, neurodegenerative diseases have become one of the world’s largest unmet medical needs. Annovis understands how the brain works and how brain cells die. Nerve cell death is the underlying cause of all neurodegenerative disease in both slow chronic and fast acute injuries to the brain.
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Our Treatments
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We are developing transformative therapies for Alzheimer’s Disease (AD), Parkinson’s (PD) and other neurodegenerative disorders. Our lead candidate, buntanetap, simultaneously inhibits the production of multiple neurotoxic brain proteins that have been shown to impair axonal transport and lead to nerve cell death. Specifically, it inhibits the synthesis of amyloid precursor protein (APP), Tau and α-Synuclein. It is distinct from other AD drugs in development, because, unlike many other drugs that attempt to remove one toxic protein, buntanetap inhibits the toxic proteins before they can form, and it inhibits all the major neurotoxic proteins responsible for AD and PD.